Thursday, April 02, 2026

The Blatant Reasons for the Destruction of NSF (and other federal science agencies)

update through March 13 2026, via Jeremy Berg

 

Trump recently announced the new roster of the US President’s Council of Advisors on Science and Technology (PCAST), which includes plenty of tech billionaires (and just one academic scientist). 

This really cements the reasons for the decimation of science in the US:

  • The tech bros have decided that AI will do everything 
  • A pathetic white christian nationalist wants to destroy “woke” science and “woke” universities
  • Deranged MAHA conspiracy theorists run the Department of Health and Human Services (HHS)

 

Today's post will discuss the first bullet point, and conclude with a catastrophic prediction. 


PCAST Appointees


“Know thyself.” (Delphic maxim, 5th or 6th century BC)

“The unexamined life is not worth living.” (Socrates, 399 BC)


1. Marc Andreessen, net worth $1.9 billion. Co-founder of venture capital firm Andreessen Horowitz (a16z). Notable for announcing his own lack of introspection and his ignorance of history (“...and if you go back 400 years ago, it never would have occurred to anybody to be introspective).”

Andreessen called for the dissolution of the National Science Foundation (NSF) in a private group chat leaked in July 2025:

Andreessen’s message to the group about subjecting the NSF to “the bureaucratic death penalty” alleged that the agency, a major funder of university science and tech labs, backed projects that led to online censorship of American citizens... The investor added: “Raze it to the ground and start over.”

 

This is despite the shocker that NSF funded the Mosaic browser, the precursor to Netscape. Andreessen was a student at the University of Illinois and worked at the National Center for Supercomputing Applications (NCSA) in 1993. In fact, the NSF website states:

In 1994, NSF awarded a large grant to NCSA specifically for Mosaic development, enhancement and support. Marc Andreessen, a member of the team that developed Mosaic, would later help found Netscape Communications.

 

When Netscape went public in 1995, Andreessen received a windfall of $56 million in stock options. And now he wants to raze the federal funding system responsible for his fortune. Not surprisingly, he also declared his disdain for DEI, immigration, Stanford, and MIT. It's laughable that such an insanely wealthy man felt the need to air his white grievances (among friends). Referring to the rise of diversity policies, he said, “And so now my people are furious and not going to take it anymore.”

“His people” (low income white students from rural areas) also lost their diversity funding when DEI grants were cancelled.


2. Sergey Brin, net worth $235 billion. Co-founder of Google. Currently working on Gemini AI. Psilocybin microdoser. Has invested in longevity research (Calico), biopharma for brain disorders (MapLight), 3D spatial multiomics (Stellaromics), ibogaine for traumatic brain injury, substance abuse, and psychiatric conditions (Soneira), CO2 removal from ambient air (280 Earth), and large-scale offshore energy hubs (Copenhagen Energy Islands). His nonprofit, Catalyst4 Inc., has donated $50 million to the Michael J. Fox Foundation for Parkinson’s Research.

Sure, Brin may be using Catalyst4 as a tax shelter for the $366 million of Tesla stock he dumped after a dispute with Elon Musk, but at least his investments are trying to help humanity, rather than kill us all.


3. Safra Catz, net worth $3.4 billion. Former CEO of Oracle. On the board of the Ellison media conglomerate Paramount Skydance. While on the board of Walt Disney Company, she threatened to fire the CEO if Strange World, an animated film featuring a gay teenager, was released. Initially donated to Marco Rubio in 2016, but has been a Trump supporter ever since. She lives in Florida. In a mansion in Isla Bahia, an exclusive gated waterfront community in Fort Lauderdale. That explains a lot.

 

4. Michael Dell, net worth $151 billion. Founder, Chair, and CEO of Dell Technologies. Dell has partnered with NVIDIA to “build the engines of AI factories.” What is an AI factory? “The AI factory transforms internal and external data into actionable insights through advanced analytics,” according to an odious blog post from Harvard Business School. Gad.

Dell and his wife will donate $6.25 billion to Trump accounts🤮, a nebulous proto-IRA investment vehicle for kids. The Dell's contribution will supposedly provide $250 each to 25 million children who live in neighborhoods where the median family income is less than $150,000.

The funds in Trump Accounts must be invested in certain mutual funds or exchange-traded funds that track the S&P 500 or another index of primarily American equities.

Once the child turns 18, the account can be converted to a traditional IRA, where early withdrawals before age 59½ may be subject to a 10% penalty. And beware the kiddie tax! Consult your financial advisor!

I know, I know, this is far removed from NSF. Which is precisely the point. Trump doesn't care about science and technology. He only cares about money and glory (however false).


5. Jacob DeWitte, net worth $1.7 billion. Founded nuclear fission company Oklo with his wife, Caroline Cochran (who is also worth $1.7 billion, according to Forbes). Cochran has a masters in nuclear engineering from MIT, and DeWitte has a Ph.D. from the same program. Oklo received venture capital from Sam Altman (OpenAI), Peter Thiel (the Antichrist), Dustin Moskovitz (Facebook), and other billionaires. Climate change denier and Trump campaign mega-contributor Chris Wright served on Oklo's board until he was confirmed as Secretary of Energy. 

In May 2025, Trump signed the executive order Deploying Advanced Nuclear Reactor Technologies. DeWitte was there to praise the dictator:

“We’re working on small, next generation reactors that take technology America invented, developed, and pioneered, and bringing it to the market after it sat on the shelves of history for about 40 years — and it’s because of the actions that you’re doing today that are going to help unleash that. Changing the permitting dynamics is going to help things move faster.”

Oklo has no revenue and $55 million in losses as of June 2025. They have no reliable source of HALEU (high-assay low-enriched uranium, also known as unobtainium) and no plan to open a plant any time soon. Meanwhile, potential demand from the overpromise of AI data centers (see Jensen Huang) may be waning. According to investment newsletter TheStreet, “Oklo remains a pre-revenue company, with valuation driven by execution milestones rather than financial results.”


6. Fred Ehrsam, net worth $2.6 billion. Co-founder of Coinbase, a cryptocurrency exchange. The Trump family made billions from their own crypto-grift, which was condemned as “corruption on a breathtaking level” and “among the greatest US scandals ever.” 

Ehrsham also poached eight employees from Neuralink and started Nudge, a start-up producing a consumer headset based on focused ultrasound. Whether it works as advertised will be an interesting topic for the future.


7. Larry Ellison, net worth $201 billion (he lost $46 billion so far this year). Founder of Oracle, where he was CEO from 1977 to 2014. Currently he's CTO and executive chair. Father of David Ellison, who owns a Trump-friendly media monopoly that censors unflattering coverage (e.g., Bari Weiss pulled the 60 Minutes episode on CECOT, the torture prison in El Salvador).

 

image via Mary Trump

 

Larry is a horrible person. In 2012 he purchased 98% of the Hawaiian island of Lānaʻi, where he acts like a plantation owner:

...Ellison is a modern American king—incomprehensibly wealthy and powerful. Many residents both rent from him and work for him, and a provision in his residential leases states that if you’re terminated from a job with any of his companies, you can be kicked out of your home, too. Under Ellison, 30-day leases have become the norm for Lanai’s small businesses, as opposed to the five-year terms some were used to before.

Accused war criminal Benjamin Netanyahu vacationed there with his family in 2021. Ellison is a prosecution witness in Netanyahu's long-delayed corruption trial, yet he forced another billionaire to drop his own lawyer in favor of defending Bibi.


8. David Friedberg, net worth $1.2 billion. Founded The Climate Corporation (an agriculture tech company), which was sold to Monsanto for $1.1 billion. In 2016 he founded The Production Board, a holding company that invests in “technology businesses across life sciences, food and agriculture, and software.” He is a proponent of the Abundance Movement and its deregulation of environmental protections. He believes AI will usher in a utopian society where everyone has free time for family and leisure. 

AI's positive outcomes are being underestimated

"Folks are underestimating and under realizing the benefits, at this stage, of what's going to come out of the AI revolution and how it's ultimately going to benefit people's availability of products, cost of goods, and access to things."


This is ridiculous, because we already have superabundance, but the billionaires refuse to share their wealth. As Gil Duran stated:

The problem with this fairy tale fantasy lie of Altman's [and others] is that we already have abundance. It's just not fairly distributed in the world. Most of it is going to a small percentage of people. And so if the people who are the profiteers of our current abundance aren't sharing it now, why the hell are they going to share it in the future?


Friedberg also co-hosts the manosphere-adjacent All-In podcast. Red-pilled and pro-MAGA:

No other show or podcast has paved the country’s path to founder mode so directly as All-In. On the heels of helping bankroll Trump’s campaign and hosting him on the pod, the Besties are becoming fixtures at the White House. Days prior to the summit, [David] Sacks and [Chamath] Palihapitiya dined there along with a coterie of Silicon Valley’s most powerful CEOs. Before Trump even took office, he appointed Sacks as the country’s “crypto and AI czar” to help shape federal policy on everything from digital money to machine intelligence.

 

9. Jensen Huang, net worth $165 billion. Founder, president, and CEO of NVIDIA, best known for its graphical processing units (GPUs), which are critical for AI. Huang received a master's degree in electrical engineering from Stanford by attending night classes. His company has a market capitalization of over $4 trillion, accounting for 7-8% of the S&P 500 index. 

Ed Zitron, the angriest tech critic, has written extensively about circular deals between NVIDIA, Oracle, OpenAI, and other behemoths. For instance, The AI Bubble's Impossible Promises:

NVIDIA invested money in a company [a special purpose vehicle] specifically built to buy chips from it, which then promptly handed the money back to NVIDIA along with a bunch of other money, and then whatever happened next is somebody else’s problem.

and The Hater's Guide To NVIDIA:

NVIDIA's Future Success Is Predicated On The Ability For Everybody To Keep Feeding It Tens Of Billions Of Dollars Every Quarter, Requiring Endless Debt, Space, and Actual AI Demand To Exist

...and the magnificent tome, The AI Industry Is Lying To You (a 37 minute read)

Speaking of which, here is Sam Altman musing that GPT-5 is already doing new science! (link to video)


This overly optimistic view has infiltrated federal agencies.

 

I'm listening in on the DOE Office of Science Advisory Committee meeting and the current speaker (sorry, did not catch their name) said that researchers are often limited in their resources and facilities, and that we could be investing more....and that the solution is AI. I'm going to explode.

— Karolina Heyduk (@kheyduk.bsky.social) March 27, 2026 at 11:04 AM


Heyduk went on to say, 

"AI can't pay my grad students or postdocs. AI can't do our experiments, collect really any of our data, make our lab reagents, fix our broken machines as they age.  ...  Actually its pretty clear from this discussion they don't see a need for the types of scientist we're training in the lab. Automated labs can do it all."

[see outsourcing of scientific research below]


  

10. John Martintis, the only academic on the panel, is currently a Professor of Physics at UC Santa Barbara. He shared the 2025 Nobel Prize in physics “for the discovery of macroscopic quantum mechanical tunnelling and energy quantisation in an electric circuit.” In 2014 he moved from UCSB to Google AI Quantum, where his research group achieved quantum supremacy: they built a programmable superconducting processor that could sample a quantum circuit a million times in 200 seconds, which would take 10,000 years with a classical supercomputer (Nature, 2019).

But in 2020, a conflict in “management styles” led Martintis to resign from Google and return to UCSB. In an interview, Martinis explained how his singular focus [and complete control over his research group] led to tension:

To explain the tension, you should understand that my personal research style tends to be very intently focused. For example, with the quantum supremacy experiment, I focused on doing the experiment because I thought it would be a milestone and very challenging, but doable. I thought it would strongly focus the group on important problems. I think it was hard on people in the group to focus on quantum supremacy because it meant they couldn't work on other things they wanted to do, and most importantly, we could fail.

And then we learn that Martinis is a fan of Peter Thiel, the Antichrist who co-founded Palantir1 

Martinis is a co-founder and CTO of Qolab, a quantum computing start-up that has raised at least $16 million in venture capital. 

 

11. Bob Mumgaard, net worth unknown. Founder and CEO of Commonwealth Fusion Systems (CFS), which has raised $3 billion in venture capital from NVIDIA, Google, Mitsubishi, Morgan Stanley, etc. Mumgaard has an M.S. in Nuclear Engineering and a Ph.D. in Applied Plasma Physics, both from MIT. CFS is a spinoff of the MIT Plasma Science and Fusion Center,2 which has received substantial federal funding.

When will fusion energy plants be fully operational? Estimates vary, depending on who you ask. Some experts say 2050, while Helion (backed by Sam Altman) projects it will provide power to OpenAI and Microsoft starting in 2028, which seems preposterous.

And how can we forget the bizarre merger of Trump's failing social media site (Truth Social) with another fusion energy company? Reminder: Trump Media & Technology Group has agreed to a more than $6 billion merger with fusion company TAE Technologies. Trump's shares increased from $400 million to about $1.6 billion. The level of corruption is unfathomable. And it goes without saying that the members of PCAST were chosen for their abilities to further enrich the Trump family.

 

12. Lisa Su, net worth 1.1 billion. President and CEO of Advanced Micro Devices (AMD) since 2014. She has a Ph.D. in Electrical Engineering from MIT, where she was one of her supervisor's best students ever. In addition to many other awards, Su was the first woman to receive the IEEE Robert Noyce Medal in 2021. She was also named to PCAST by Biden and is the only bipartisan choice. She and Martinis were praised by a former member of the panel.


13. Mark Zuckerberg, net worth $220 billion.3 Tries very hard to be a cool guy with the in-crowd, but it just never works. I recommend watching the Zuckerberg episode of This F*cking Guy on YouTube. Hysteria’s research is thorough, covering everything from nerd beginnings to failed products (like the entire Metaverse) to Facebook-fueled genocides to Republican political shenanigans (the Cambridge Analytica scandal) to his newfound embrace of masculinity.


Catastrophic Consequences

It's a slow march to the death of federal funding for basic research in the US. "Innovation" and "dominance" are code words for enriching the billionaires. American Dynamism represents a16z's push for privatization and for billions of dollars in military contracts, paid for by your tax dollars (if you're in the bottom 90% or so). Invest in visionary defense tech founders, not in education or healthcare.

COMMERCIAL FIRST

Make procurement of commercial items using commercial procedures the default for DOD acquisitions absent a documented need for a defense-specific system. America’s Founders are delivering superior commercial solutions at significantly lower cost. Those commercial solutions should be the default.


Compare this to basic science last. From Science magazine, 16 Mar 2026:

What’s happening to NSF now highlights how this year’s process differs. Last month, each account within the agency—NSF has six—received its own apportionment [limits on the dispersal of agency funds]. ...  But NSF’s two biggest accounts—$7 billion for research and $1 billion for science education—came with footnotes that could lead to potentially devastating consequences for researchers.

 

Only 613 NSF grants have been awarded in the first half of FY2026 (Oct 1 2025 – Mar 31 2026), an 80% decrease from 2021 – 2024.



Meanwhile, the outsourcing of scientific research to AI has begun.

Genesis Mission to Accelerate AI for Scientific Discovery 

Harnessing AI as a scientific tool will revolutionize the way scientific research is conducted.
  • For example, AI technologies can generate models of protein structures and novel materials, design and analyze experiments, and aggregate and generate new data faster and more effectively. Research that once took years could now take weeks or months.

 

Generate new data. To replace bench work? To supersede all neuroimaging modalities? How, exactly, is that supposed to happen? At present, large language models (LLMs) are poor at answering expert level academic questions.

A consortium of researchers compiled a list of 2,500 challenging questions covering math, physics, biology, computer science, humanities, engineering, and chemistry (Nature, 2026). The authors called this Humanity's Last Exam (HLE). And the models they tested had very low accuracy.



Even if performance was adequate, this would not indicate that LLMs possess “artificial general intelligence” (as claimed by tech oligarchs everywhere) or even autonomous research capabilities (Nature, 2026):

High accuracy on HLE would demonstrate expert-level performance on closed-ended, verifiable questions and cutting-edge scientific knowledge, but it would not alone suggest autonomous research capabilities or artificial general intelligence. HLE tests structured academic problems rather than open-ended research or creative problem-solving abilities, making it a focused measure of technical knowledge and reasoning across a diverse range of subjects...


Introspection...


Footnotes

1 The interviewer, Paul Smith-Goodson, takes a sidebar to tell the reader that Martinis subscribes to the Peter Thiel definition of personality. 

At this point, Professor Martinis asked me if I had read Peter Thiel's book, Zero to One. Thiel was a co-founder of PayPal and Palantir. He explained that Peter Thiel defines personality styles as either a definite optimist or indefinite optimist. Professor Martinis considers himself to be a definite optimist. One quote from Thiel's book seems to mirror his thinking: “…a definite person determines the one best thing to do and then does it.” I admitted that I started the book but failed to finish it.  

2 As an aside, the director (Nuno Loureiro) was murdered by the Brown University shooter in a separate incident.


3 These amounts can vary wildly day by day (Zuckerberg is just under $200 $196 billion). Track the billionaires net worth in real time!

 


seen at No Kings on March 28, 2026

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Thursday, March 05, 2026

RETRACTED FOR THE SECOND TIME: phony study on "biofield energy" treatment


It was an unusual decision to republish an already-retracted paper in a different journal, but Wiley has retracted (again) the purported effects of a supernatural “intervention” on biological and emotional health.

Dr. Ioana A Cristea's comments on PubPeer (conveyed to the journal) and my letter to the Editorial Staff (posted on this blog on December 29, 2025) triggered an investigation that ultimately led to the retraction:


RETRACTION: M. K. Trivedi, A. Branton, D. Trivedi, S. Mondal and S. Jana, “Amelioration of Adults' Mental Health Conditions and Symptoms Through Spiritual Energy Therapy: Randomized Controlled Trial,” Neuropsychopharmacology Reports 45, no. 3 (2025): e70050, https://doi.org/10.1002/npr2.70050

The above article, published online on 10 September 2025 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Tsuyoshi Miyakawa; The Japanese Society of Neuropsychopharmacology; and John Wiley & Sons Australia, Ltd. The retraction has been agreed upon as a similar version of this article by the same authors was previously retracted by the Journal of General and Family Medicine (https://doi.org/10.1002/jgf2.773). Although revisions have been made, the article does not adequately address the previously identified concerns. In particular, issues regarding the appropriateness of the control group and the psychological questionnaire scoring method remain unresolved. Additionally, some biomarker values remain implausible without sufficient justification and claims regarding the efficacy of spiritual energy therapy continue to lack independent supporting evidence. The editors agree the results and conclusions are unreliable. The authors disagree with the retraction.


And once again, “The authors disagree with the retraction.”

What were some of the issues?

The problematic values [of klotho, an anti-aging protein] are magnified in Appendix 2, see the Table 3 & 4_Biomarker_Control tab for ’Spiritual Energy Therapy Group (Day 180)’. In the Klotho column, 28 out of 35 participants have values of 20.00 ng/mL. This is the upper limit of the assay, according to ThermoFisher (https://www.thermofisher.com/elisa/product/Human-Klotho-ELISA-Kit/EEL200). Importantly, 20.00 ng/mL is 8.73 to 27 times above the upper 95th percentile.  


...and of course:

  • The Trivedi Effect® has not been scientifically proven. Citations #14 and #15 provided no data to support this.

The Trivedi Effect®” is Mahendra Kumar Trivedi's patented form of “Biofield Energy Treatment”

An extraordinary, unprecedented and evidence-based phenomenon that can transform the cellular structure of living organisms, alter atomic structure of non-living materials and revolutionize an individual’s life.  

These assertions are indeed extraordinary — they are not evidence-based. They have never been scientifically proven. They do not belong in any literature that claims to be scientific.

There's a long list of other papers that should be retracted (a set of six more, for starters), but I still have a regular (paying) job.

 

Further Reading

The Miraculous Guru with an h-index of 62

Backed by Science? Building a lucrative spiritual empire based on potentially “questionable” publications

RETRACTED: phony study on "biofield energy" treatment by a Guru

The Guru Republishes Retracted Paper in Another Exploitable Journal

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Tuesday, January 27, 2026

The Organized Destruction of Empathy


Over the past year, US residents have been subjected to the abuses of an increasingly lawless authoritarian state. Our constitutional rights are violated on a daily basis.1 How did we get here? 

The denigration of respect and concern for our fellow humans has been instrumental. Whether we want to consider moral philosophy, everyday expressions of empathy and compassion, or religious edicts such as “Do unto others as you would have them do unto you” (Luke 6:31), the actions of Homeland Security (ICE), the State Department, CDC, DOGE, etc. have exemplified the callous disregard for human life.

This has been quite ironic, since much of the wreckage has been done in the name of a punitive, perverted version of Christianity practiced by white christian nationalists such as Russell Vought, the OMB bureaucrat who vowed to traumatize federal employees (reported by ProPublica in 2024):

“We want the bureaucrats to be traumatically affected,” he said. “When they wake up in the morning, we want them to not want to go to work because they are increasingly viewed as the villains. We want their funding to be shut down so that the EPA can’t do all of the rules against our energy industry because they have no bandwidth financially to do so.

“We want to put them in trauma.”


Elon Musk, the notoriously unempathetic billionaire, gleefully put USAID in the woodchipper. A year later, an estimated 757,314 people have died from the funding cuts.

 

As Adam Serwer wrote back in 2018:

The Cruelty is the Point 

. . .

The Trump era is such a whirlwind of cruelty that it can be hard to keep track. This week alone, the news broke that the Trump administration was seeking to ethnically cleanse more than 193,000 American children of immigrants whose temporary protected status had been revoked by the administration, that the Department of Homeland Security had lied about creating a database of children that would make it possible to unite them with the families the Trump administration had arbitrarily destroyed, that the White House was considering a blanket ban on visas for Chinese students, and that it would deny visas to the same-sex partners of foreign officials.

 

And it's gotten much, much worse. 2  


Detained Immigrants Detail Physical Abuse and Inhumane Conditions at Largest Immigration Detention Center in the U.S.
...interviews with 45 people report physical and sexual abuse, medical neglect, and intimidation to self-deport.

Immigrant families protest inside Texas facility housing 5-year-old boy, father detained in Minnesota

AP Photo/Brenda Bazán

AP Photo/Damian Dovarganes

Kaden Rummler said in an interview that he was in agonizing pain and underwent an extensive six-hour surgery to his left eye after he was injured at a Jan. 9 protest over the fatal shooting of a woman by an Immigration and Customs Enforcement officer in Minneapolis. Rummler said he has no depth perception and can no longer drive.

 

[The video is horrible to watch. Other protesters have been blinded by these "less lethal" weapons. Another had a finger blown off.]

 


And then we have cosplay Kristi, in a staged photo-op, posing in front of actual Salvadorian gang members who have been imprisoned in CECOT for years. NONE OF THEM WERE DEPORTED FROM THE US, according to the CBS-censored 60 Minutes episode. Another lie, another piece of social media propaganda for DHS.


The Lies

They're too numerous to mention.3 Don't believe your own eyes... Kristi says that ICE agents feared for their lives when Alex Pretti brandished a gun [i.e., took video with his phone], so it must be true.

This looks like a situation where an individual arrived at the scene to inflict maximum damage on individuals and to kill law enforcement.



“The Party told you to reject the evidence of your eyes and ears. It was their final, most essential command.” 

― George Orwell, 1984

Footnote
 

1 Free speech (1st amendment), the right to assemble (1st), imposition of religion (also 1st – see supposed discrimination against Christians and state-sponsored services with Pete Hegseth's misogynistic pastor), probable cause (4th), due process (5th), and birthright citizenship (14th), for starters. 

Plus  new!  the Second Amendment!

Are guns barred at protests, as Kash Patel said? In most states, no

“You cannot bring a firearm loaded with multiple magazines to any sort of protest that you want. It’s that simple.”

Compare to these election denialists on January 17, 2021.
 

Scott Olson/Getty Images 

Armed demonstrators protest outside of the Michigan state capital building in Lansing, Michigan. 

 


2 I started this blog 20 years ago with a post on empathy for another person's (faux) pain. Lynndie England and the torture at Abu Ghraib were featured.

Men are Torturers, Women are Nurturers...
 
 

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Wednesday, December 31, 2025

Neurosocieties Unknown

Chris Skinner poster of ‘Dark City’


I’m finally starting a newsletter!! Neurocritical Thoughts will function as a supplementary “trial” blog, with summary content cross-posted here. My initial focus will be on the delusions of tech billionaires — things like mind uploading, life extension, cryogenic preservation, “vibe physics”, and overblown predictions that GPT-6 will create “new science.”

Other posts will feature the latest in brain recording and stimulation technology, from the awesome to the awful. I’ll try to keep most pieces on the shorter side, so please sign up for the free newsletter. Or else find the posts via my social media feeds.

 


 

Subscribe here!

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Monday, December 29, 2025

The Guru Republishes Retracted Paper in Another Exploitable Journal

image from Google Scholar


Remember Guruji Mahendra Kumar Trivedi, the “Enlightened and miraculous being” with 676 publications in scientific journals? His patented form of “Biofield Energy Treatment” is called “The Trivedi Effect®”.

An extraordinary, unprecedented and evidence-based phenomenon that can transform the cellular structure of living organisms, alter atomic structure of non-living materials and revolutionize an individual’s life.  

 

These assertions are indeed extraordinary — they are supernatural, not evidence-based. They have never been scientifically proven. They do not belong in any literature that claims to be scientific.

Trivedi and his colleagues are masterful at abusing a broken publication system. The Guru has a high h-index (62) and 12,969 citations of his work. The h-index is a metric that considers an author's productivity and the citation impact of their publications. However, it is easily manipulated. Most of Trivedi's “impact” is from self-citations in a tangled web of predatory journals that publish questionable papers without proper peer review. 

And like Joe Dispenza, Guruji benefits financially from faith healing under the guise of science.

Guruji’s Blessing has impacted the lives of hundreds of thousands of people globally, and has been validated globally with cutting-edge scientific research.


Except his published science is not valid and has no basis in physical reality. That doesn't stop his organization from offering monthly memberships, ranging from $250 per month for 1 remote blessing to $10,000 per month for the Platinum Path to Enlightenment Membership.

 


Republishing Retracted Nonsense

I have never seen a journal publish a paper that was retracted from another journal. Yet here we are, and John Wiley & Sons, Inc. is responsible for both cases.
 


 
The authors objected to the retraction from the Journal of General and Family Medicine and issued a Disclaimer Statement in Neuropsychopharmacology Reports
The manuscript submitted under ID NPPR-2025-0089 is a corrected, thoroughly revised, and edited version of the previously retracted paper published in J Gen Fam Med, 2023; 24: 154–163. The authors seek to republish it because they disagree with the journal's decision to retract the paper, which was based on objections from a third-party complainant. In the original retraction notice, the authors expressed their disagreement with the retraction. This newly submitted article (NPPR-2025-0089) has been rewritten and corrected for typographical errors. Additionally, it no longer includes data on a few biomarkers that raised concerns in the retracted article due to the high variability observed in these biomarker values.

The revised paper is still quite problematic. My Letter to the Editor and Publisher is reprinted below, formatted for the blog.


-- start of letter --

December 28, 2025      

Dr. Miyakawa and the Editorial Staff of Neuropsychopharmacology Reports,

 I am writing about the legitimacy of an article published in the journal:
Trivedi, M. K., Branton, A., Trivedi, D., Mondal, S., & Jana, S. (2025). Amelioration of Adults' Mental Health Conditions and Symptoms Through Spiritual Energy Therapy: Randomized Controlled Trial. Neuropsychopharmacology Reports, 45(3), e70050.

This paper was retracted from the Journal of General and Family Medicine after an investigation:
The retraction has been agreed upon following an investigation into concerns raised by a third party, which revealed an inappropriate control group used as the placebo group of the trial, inconsistencies in the Psychological Questionnaire Scoring, highly implausible functional biomarker values that are out of the typical physiological range, and unsupported claims regarding the scientific evidence behind the biofield energy treatment.

The authors objected to the retraction, edited the manuscript, and submitted it for publication in NPPR. The first author still makes extraordinary and unvalidated claims about his ability to change the mental and physical health of human volunteers via transmission of his thoughts (described as “blessing” throughout the manuscript). A peer-reviewed journal that accepts such declarations without incontrovertible scientific evidence, which was never provided, has compromised its scientific reputation. Furthermore, the study’s design is flawed and much of the data contained in the paper is implausible and inauthentic.

I am an established scientist who runs a research lab, and as I will outline below, it is ethically mandatory for Neuropsychopharmacology Reports to reconsider this paper and for Wiley to retract it from the scientific literature for the following reasons. 

  1. In the abstract, the paper contends that the study was a “single-blind, active-controlled, randomized trial.” This is false.
  2. Control subjects did not receive any treatment.” (p. 2)

  3. The psychological questionnaire (PQ) used to assess mental health was “…based on a 7-point Likert scale of scoring” with two questions for each of 14 symptoms (see p. 3 and Appendix 1).
  4. “The PQ was made by in-house renowned experienced psychologists based on literature with some modifications, and these PQs were routinely used in various clinical trial projects.”

    There are many standardized psychological instruments that could have been used (e.g., PHQ-9, Beck Depression Inventory, Pittsburg Sleep Quality Index), but the authors chose to use an unvalidated measure (file ‘npr270050-sup-0001-annexures1.docx’) with some unusual questions such as, “How is the quality of your skin?” for sleep disturbances and “Do you have desire to become independent and do something big for your family?” for Lack of inspiration, which would need to be reverse scored. Furthermore, the questions for Emotional Trauma do not measure emotional trauma.

    The authors added Appendix 2 (file ‘npr270050-sup-0002-datas1.xlsx’) to the republished paper, which contains the raw data. However, the Table 2 data contain some irregularities. In the Table 2_PQ_Treatment tab, the scores for ‘Stress from the Spiritual Energy Therapy Group (Day 180)’ are all ‘2’. It is statistically unlikely that 35 people would all endorse the lowest possible score for those two questions. For Sleep Disturbances, 32 out of 35 scored ‘2’ and for Depression, 30 out of 35 scored ‘2’.

  5. Tables 3 and 4 list measurements for the functional biomarkers, which are the clearest evidence for unverifiable data (or error). In the retracted paper, some of these were highly implausible, because their values were out-of-range of typical physiological levels (to an extent beyond what is seen in pathological conditions). Oxytocin and plasma catecholamines (dopamine and norepinephrine) were the most egregious, and they were omitted from the revised paper, which... 
  6. …no longer includes data on a few biomarkers that raised concerns in the retracted article due to the high variability observed in these biomarker values.

    The problem wasn’t high variability, it was that the values were physiologically impossible. For the remaining biomarkers, clarifications were made (e.g., 17-β-estradiol was measured only in women and the units were ng/L, not ng/mL). 

In the example below, the units for Klotho (an anti-aging biomarker) were revised from pg/mL to ng/mL, but now the values are much above normal.
 

Group/treatment

Klotho (ng/mL)

Control (N = 42)

Mean of Days 0,  90, and 180

2.25 ± 0.04

 

Spiritual Energy Therapy (N = 35)

Day 90

11.09 ± 0.39

 

Day 180

17.67 ± 0.99

 

normal values α-Klotho (converted to ng/mL)

                    Mean         SD         Ref Interval (2.5–97.5th %ile)
ELISA          0.472        0.136        0.204 to 0.741
(n = 126) 
 

                    Mean          SD        Ref Interval (5–95th %ile)
Age 18–35    0.933        0.576        0.393 to 2.292
(n = 167)

 
The problematic values are magnified in Appendix 2, see the Table 3 & 4_Biomarker_Control tab for ’Spiritual Energy Therapy Group (Day 180)’. In the Klotho column, 28 out of 35 participants have values of 20.00 ng/mL. This is the upper limit of the assay, according to ThermoFisher (https://www.thermofisher.com/elisa/product/Human-Klotho-ELISA-Kit/EEL200). Importantly, 20.00 ng/mL is 8.73 to 27 times above the upper 95th percentile.
 
Other irregularities abound. In a meta-analysis of 12 studies, the normal level of TNF-α was 5.5 pg/mL (Gharamti et al., 2022). At Day 0 for the Treatment Group, 28 out of 35 participants had a value of 0.00, while one person had a value of 218.58 pg/mL, which would be indicative of severe inflammation. At Day 180, 32 of 35 participants had a value of 0.00. Similar improbable findings can be seen for IL-1β.

Finally, the Treatment Group at Day 90 & Day 180 should have been compared to Controls at Day 90 & Day 180, not to the mean of Days 0, 90, and 180 for Controls.


4. The paper presents supernatural phenomena as real (p. 2):
“The Trivedi Effect is one of the scientifically validated and widely reported spiritual energy healing approaches (one form of biofield energy therapy), based on data from preclinical (cell-based and animal-based) and clinical (human) studies [14, 15]. Trivedi healing practitioners can harness the consciousness energy from the universe and transfer it to both living and non-living objects through their unique inherent thought transmission process in a positive way; this phenomenon is called The Trivedi Effect.”

  • The Trivedi Effect® has not been scientifically proven. Citations #14 and #15 provided no data to support this.

And on p. 7:
“Recent studies propose that biofield energy therapies may involve a spiritual aspect that operates at the quantum level through the healer's energy and thoughts, leading to healing through instantaneous communication at the quantum level via quantum entanglement [44]. Quantum entanglement allows for instantaneous connection between separated system elements and can be utilized for signaling across vast distances [47].”

As Dr. Ioana Cristeta stated on PubPeer:
“…unsupported claims remain, including an entire paragraph in the Discussion speculating how quantum entanglement, a construct never before applied to humans (or for that matter any solid object), would explain the effects of spiritual energy therapy. The Discussion is rife with unscientific, never proven or even operationalized constructs, such as energy transmission, remote communication, bioresonance and others.” 

5. On its website, Wiley endorses the Committee on Publication Ethics (COPE) guidelines and provides links to the Core Practices for journals and publishers:


As I have demonstrated, the claims in Trivedi et al. (2025) are beyond the realm of empirical science, and a reputable medical journal should not publish them. Wiley, as a supporter of COPE, should subscribe to ethical standards in peer review and follow the official guidelines for considering whether a retraction is appropriate. 


Sincerely,

[my real name]



Links and References

COPE. Retraction guidelines. https://publicationethics.org/guidance/guideline/retraction-guidelines [retrieved on 12/28/2025]

Espuch-Oliver, A., Vázquez-Lorente, H., Jurado-Fasoli, L., de Haro-Muñoz, T., Díaz-Alberola, I., López-Velez, M. D. S., ... & Amaro-Gahete, F. J. (2022). References values of soluble α-klotho serum levels using an enzyme-linked immunosorbent assay in healthy adults aged 18–85 years. Journal of clinical medicine, 11(9), 2415. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101232/

Gharamti, A. A., Samara, O., Monzon, A., Montalbano, G., Scherger, S., DeSanto, K., ... & Shapiro, L. (2022). Proinflammatory cytokines levels in sepsis and healthy volunteers, and tumor necrosis factor-alpha associated sepsis mortality: A systematic review and meta-analysis. Cytokine, 158, 156006. https://www.sciencedirect.com/science/article/pii/S1043466622002150

Invitrogen. Human Klotho ELISA Kit. https://www.thermofisher.com/elisa/product/Human-Klotho-ELISA-Kit/EEL200 [retrieved on 12/28/2025]

Pedersen, L., Pedersen, S. M., Brasen, C. L., & Rasmussen, L. M. (2013). Soluble serum Klotho levels in healthy subjects. Comparison of two different immunoassays. Clinical biochemistry, 46(12), 1079-1083. https://pubmed.ncbi.nlm.nih.gov/23707222/

PubPeer. Ioana A Cristea, Comment #1 on: Amelioration of Adults' Mental Health Conditions and Symptoms Through Spiritual Energy Therapy: Randomized Controlled Trial. https://pubpeer.com/publications/4BDA80E4057E201A7742E9F3B320B1 [retrieved on 12/28/2025]

Wiley Author Services. Best Practice Guidelines on Research Integrity and Publishing Ethics. https://authorservices.wiley.com/ethics-guidelines/index.html [retrieved on 12/28/2025]


-- end of letter --




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