tag:blogger.com,1999:blog-21605329.post8196855604836397236..comments2024-03-22T00:30:09.536-07:00Comments on The Neurocritic: Tylenol Doesn't Really Blunt Your EmotionsThe Neurocritichttp://www.blogger.com/profile/08010555869208208621noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-21605329.post-80156041351353460272015-05-06T10:12:59.929-07:002015-05-06T10:12:59.929-07:00Dr. R -- Thanks for your comment. I agree that hon...Dr. R -- Thanks for your comment. I agree that honest reporting should be encouraged (even if it leads to questioning and, uh, criticism). <br /><br />If you run an experiment and it fails and then you re-run it, what do you say about your original power estimate? That it was overly optimistic?<br /><br />There were quite a number of comparisons in this paper, and two main measures - picture evaluations and emotional arousal ratings, which were done sequentially. The latter were generic: “To what extent does this picture make you feel an emotional reaction?”<br /><br />Did you check both measures? Main effects of treatment and interactions? The contrast analyses? Seems to me the strongest effect was to lower ratings for extremely positive stimuli; effects on extremely negative stimuli were weaker.The Neurocritichttps://www.blogger.com/profile/08010555869208208621noreply@blogger.comtag:blogger.com,1999:blog-21605329.post-61635292383783586992015-05-05T18:26:50.545-07:002015-05-05T18:26:50.545-07:00You make a lot of good points, but combining the t...You make a lot of good points, but combining the two studies is not a problem. It is good practice to increase power (Schimmack, 2012). <br /><br />The authors report the results separately for each study. One study shows a non-significant result. The other shows a significant result. This is to be expected when a real effect is present and power is modest. In fact, observed power for the two studies averages 56%, which is consistent with one significant and one non-significant result. <br /><br />Combined the total sample has over 80% power and the significant effect for average arousal ratings is statistically credible. <br /><br />Based on the reported results, there is no statistical reason to doubt that Tylanol lowered arousal ratings. <br /><br />Of course, it would still be nice to have an independent replication study, but this is not a bad study given sample size and honest reporting of non-significant results in Study 1. <br />Dr. Rhttps://replicationindex.wordpress.com/noreply@blogger.com