tag:blogger.com,1999:blog-21605329.post2357261515258310349..comments2024-03-14T23:52:09.893-07:00Comments on The Neurocritic: Does Tylenol Exert its Analgesic Effects via the Spinal Cord?The Neurocritichttp://www.blogger.com/profile/08010555869208208621noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-21605329.post-5303940950331470152013-04-24T10:15:12.861-07:002013-04-24T10:15:12.861-07:00Thanks! Interesting observation. It seems to me th...Thanks! Interesting observation. It seems to me that a reduction in physical pain could result in a calmer demeanor, and hence fewer negative thoughts racing through your mind upon awakening. That's a pretty vulnerable time, because the full force of frontal lobe "cognitive control" processes aren't immediately online yet. If there's less bodily tension, lower autonomic arousal, and less pain, perhaps this blunting of illness results in a more relaxed state.<br /><br />This would be an indirect effect of the drug, rather than the drug acting directly on brain areas that lower anxiety.The Neurocritichttps://www.blogger.com/profile/08010555869208208621noreply@blogger.comtag:blogger.com,1999:blog-21605329.post-48966079364252264072013-04-23T12:42:16.755-07:002013-04-23T12:42:16.755-07:00Great post NC. I just wanted to report something a...Great post NC. I just wanted to report something anecdotal. Often I wake up in the middle of the night and experience serious anxiety. You know, the kind in which everything is doomed and there is nothing to do about it. However, if I take Tylenol before going to bed, when I wake up, the same thoughts go through my mind, but they do not have the same negative connotation. It is really like knowing that there is pain there but not perceiving it. I do not take Tylenol for this reason, I just noticed this effect consistently when I take it. It could be that perhaps I take Tylenol when I have a cold and the illness is the real cause of the effect. Very curious. Anonymousnoreply@blogger.com